Targeting casein kinase 1 delta sensitizes pancreatic and bladder cancer cells to gemcitabine treatment by upregulating deoxycytidine kinase

Although gemcitabine is the cornerstone of care for pancreatic ductal adenocarcinoma (PDA), patients lack durable responses and relapse is inevitable. While the underlying mechanisms leading to gemcitabine resistance are likely to be multifactorial, there is a strong association between activating g...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer Ther
Egile Nagusiak: Vena, Francesca, Bayle, Simon, Nieto, Ainhoa, Quereda, Victor, Aceti, Massimiliano, Frydman, Sylvia M., Sansil, Samer S., Grant, Wayne, Monastyrskyi, Andrii, McDonald, Patricia, Roush, William R., Teng, Mingxiang, Duckett, Derek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415672/
https://ncbi.nlm.nih.gov/pubmed/32430484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0997
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