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Oncogenic KRAS Drives Metabolic Vulnerabilities by Directly Regulating Metabolic Enzymes in Cancer
Metabolic reprogramming, such as enhanced aerobic glycolysis, allows cancer cells to maintain viability and promote proliferation. It is one of the major consequences of oncogenic mutations. KRAS is the most frequently mutated oncogene in human cancer. It is thought to be closely related to metaboli...
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| 發表在: | Glob Med Genet |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Georg Thieme Verlag KG
2020
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7410093/ https://ncbi.nlm.nih.gov/pubmed/32879916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1712456 |
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