Llwytho...
Metabolic vulnerability of KRAS-driven cancer cells
Interfering with anaplerotic utilization of glutamine (Gln) was recently reported to sensitize KRAS-driven cancer cells to the cytotoxic effects of capecitabine and paclitaxel. This effect was due to bypass of a Gln-dependent G(1) cell cycle checkpoint in these cells. This study highlights therapeut...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Cell Oncol |
|---|---|
| Prif Awdur: | |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Taylor & Francis
2014
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655600/ https://ncbi.nlm.nih.gov/pubmed/26609545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.963445 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|