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Oncogenic KRAS Drives Metabolic Vulnerabilities by Directly Regulating Metabolic Enzymes in Cancer

Metabolic reprogramming, such as enhanced aerobic glycolysis, allows cancer cells to maintain viability and promote proliferation. It is one of the major consequences of oncogenic mutations. KRAS is the most frequently mutated oncogene in human cancer. It is thought to be closely related to metaboli...

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Bibliografiske detaljer
Udgivet i:Glob Med Genet
Hovedforfatter: Zhang, Liyi
Format: Artigo
Sprog:Inglês
Udgivet: Georg Thieme Verlag KG 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410093/
https://ncbi.nlm.nih.gov/pubmed/32879916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1712456
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