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Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis
Oncogenic KRAS is the key driver of pancreatic ductal adenocarcinoma (PDAC). We previously described a role for KRAS in PDAC tumor maintenance through rewiring of cellular metabolism to support proliferation. Understanding the details of this metabolic reprogramming in human PDAC may provide novel t...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251888/ https://ncbi.nlm.nih.gov/pubmed/30470748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07472-8 |
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