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KRAS: feeding pancreatic cancer proliferation
Oncogenic KRAS mutation is the signature genetic event in the progression and growth of pancreatic ductal adenocarcinoma (PDAC), an almost universally fatal disease. Although it has been appreciated for some time that nearly 95% of PDAC harbor mutationally activated KRAS, to date no effective treatm...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3955735/ https://ncbi.nlm.nih.gov/pubmed/24388967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.12.004 |
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