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KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer

RAS genes (HRAS, KRAS, and NRAS) comprise the most frequently mutated oncogene family in human cancer. With the highest RAS mutation frequencies seen with the top three causes of cancer deaths in the United States (lung, colorectal, and pancreatic cancer), the development of anti-RAS therapies is a...

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Bibliografske podrobnosti
izdano v:Cold Spring Harb Perspect Med
Main Authors: Waters, Andrew M., Der, Channing J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995645/
https://ncbi.nlm.nih.gov/pubmed/29229669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031435
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