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KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers with a dismal 7% 5-year survival rate and is projected to become the second leading cause of cancer-related deaths by 2020. KRAS is mutated in 95% of PDACs and is a well-validated driver of PDAC growth and maintenance. However, d...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Zeitouni, Daniel, Pylayeva-Gupta, Yuliya, Der, Channing J., Bryant, Kirsten L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846854/
https://ncbi.nlm.nih.gov/pubmed/27096871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8040045
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