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KRAS: feeding pancreatic cancer proliferation

Oncogenic KRAS mutation is the signature genetic event in the progression and growth of pancreatic ductal adenocarcinoma (PDAC), an almost universally fatal disease. Although it has been appreciated for some time that nearly 95% of PDAC harbor mutationally activated KRAS, to date no effective treatm...

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Podrobná bibliografie
Hlavní autoři: Bryant, Kirsten L., Mancias, Joseph D., Kimmelman, Alec C., Der, Channing J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955735/
https://ncbi.nlm.nih.gov/pubmed/24388967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.12.004
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