Oncogenic Kras drives invasion and maintains metastases in colorectal cancer

Human colorectal cancer (CRC) is a major cause of cancer mortality and frequently harbors activating mutations in the KRAS gene. To understand the role of oncogenic KRAS in CRC, we engineered a mouse model of metastatic CRC that harbors an inducible oncogenic Kras allele (Kras(mut)) and conditional...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Boutin, Adam T., Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V., Cheung, Hannah, Chu, Gerald C., Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y. Alan, Kwong, Lawrence N., DePinho, Ronald A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2017
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358757/
https://ncbi.nlm.nih.gov/pubmed/28289141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.293449.116
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia