A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer

Lysosomal enzymes are synthesized in the endoplasmic reticulum (ER) and transferred to the Golgi complex by interaction with the Batten disease protein CLN8 (ceroid lipofuscinosis, neuronal, 8). Here we investigated the relationship of this pathway with CLN6, an ER-associated protein of unknown func...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Bajaj, Lakshya, Sharma, Jaiprakash, di Ronza, Alberto, Zhang, Pengcheng, Eblimit, Aiden, Pal, Rituraj, Roman, Dany, Collette, John R., Booth, Clarissa, Chang, Kevin T., Sifers, Richard N., Jung, Sung Y., Weimer, Jill M., Chen, Rui, Schekman, Randy W., Sardiello, Marco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2020
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410054/
https://ncbi.nlm.nih.gov/pubmed/32597833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130955
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia