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CLN8 is an ER cargo receptor that regulates lysosome biogenesis

Organelle biogenesis requires proper transport of proteins from their site of synthesis to their target subcellular compartment(1–3). Lysosomal enzymes are synthesized in the endoplasmic reticulum (ER) and traffic through the Golgi complex before being transferred to the endolysosomal system(4–6), b...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: di Ronza, Alberto, Bajaj, Lakshya, Sharma, Jaiprakash, Sanagasetti, Deepthi, Lotfi, Parisa, Adamski, Carolyn Joy, Collette, John, Palmieri, Michela, Amawi, Abdallah, Popp, Lauren, Chang, Kevin Tommy, Meschini, Maria Chiara, Leung, Hon-Chiu Eastwood, Segatori, Laura, Simonati, Alessandro, Sifers, Richard Norman, Santorelli, Filippo Maria, Sardiello, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277210/
https://ncbi.nlm.nih.gov/pubmed/30397314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0228-7
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