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CLN8 is an ER cargo receptor that regulates lysosome biogenesis
Organelle biogenesis requires proper transport of proteins from their site of synthesis to their target subcellular compartment(1–3). Lysosomal enzymes are synthesized in the endoplasmic reticulum (ER) and traffic through the Golgi complex before being transferred to the endolysosomal system(4–6), b...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277210/ https://ncbi.nlm.nih.gov/pubmed/30397314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0228-7 |
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