CLN8 is an ER cargo receptor that regulates lysosome biogenesis

Organelle biogenesis requires proper transport of proteins from their site of synthesis to their target subcellular compartment(1–3). Lysosomal enzymes are synthesized in the endoplasmic reticulum (ER) and traffic through the Golgi complex before being transferred to the endolysosomal system(4–6), b...

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發表在:Nat Cell Biol
Main Authors: di Ronza, Alberto, Bajaj, Lakshya, Sharma, Jaiprakash, Sanagasetti, Deepthi, Lotfi, Parisa, Adamski, Carolyn Joy, Collette, John, Palmieri, Michela, Amawi, Abdallah, Popp, Lauren, Chang, Kevin Tommy, Meschini, Maria Chiara, Leung, Hon-Chiu Eastwood, Segatori, Laura, Simonati, Alessandro, Sifers, Richard Norman, Santorelli, Filippo Maria, Sardiello, Marco
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277210/
https://ncbi.nlm.nih.gov/pubmed/30397314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0228-7
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