MUC1-C drives stemness in progression of colitis to colorectal cancer

Colitis is associated with the development of colorectal cancer (CRC) by largely undefined mechanisms that are critical for understanding the link between inflammation and cancer. Intestinal stem cells (ISCs) marked by leucine-rich repeat–containing G protein–coupled receptor 5 (LGR5) expression are...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Li, Wei, Zhang, Ning, Jin, Caining, Long, Mark D., Rajabi, Hasan, Yasumizu, Yota, Fushimi, Atsushi, Yamashita, Nami, Hagiwara, Masayuki, Zheng, Rongbin, Wang, Jin, Kui, Ling, Singh, Harpal, Kharbanda, Surender, Hu, Qiang, Liu, Song, Kufe, Donald
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406273/
https://ncbi.nlm.nih.gov/pubmed/32427590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137112
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