MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells

The polybromo-associated PBAF (SWI/SNF) chromatin remodeling complex, which includes PBRM1, ARID2, and BRD7, regulates cell differentiation and genomic integrity. MUC1-C is an oncogenic protein that drives lineage plasticity in prostate cancer (PC) progression. The present work demonstrates that MUC...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Hagiwara, Masayuki, Fushimi, Atsushi, Yamashita, Nami, Bhattacharya, Atrayee, Rajabi, Hasan, Long, Mark D., Yasumizu, Yota, Oya, Mototsugu, Liu, Song, Kufe, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321896/
https://ncbi.nlm.nih.gov/pubmed/34163028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01899-y
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