MUC1-C drives stemness in progression of colitis to colorectal cancer

Colitis is associated with the development of colorectal cancer (CRC) by largely undefined mechanisms that are critical for understanding the link between inflammation and cancer. Intestinal stem cells (ISCs) marked by leucine-rich repeat–containing G protein–coupled receptor 5 (LGR5) expression are...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Li, Wei, Zhang, Ning, Jin, Caining, Long, Mark D., Rajabi, Hasan, Yasumizu, Yota, Fushimi, Atsushi, Yamashita, Nami, Hagiwara, Masayuki, Zheng, Rongbin, Wang, Jin, Kui, Ling, Singh, Harpal, Kharbanda, Surender, Hu, Qiang, Liu, Song, Kufe, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406273/
https://ncbi.nlm.nih.gov/pubmed/32427590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137112
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