MUC1-C drives stemness in progression of colitis to colorectal cancer

Colitis is associated with the development of colorectal cancer (CRC) by largely undefined mechanisms that are critical for understanding the link between inflammation and cancer. Intestinal stem cells (ISCs) marked by leucine-rich repeat–containing G protein–coupled receptor 5 (LGR5) expression are...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Li, Wei, Zhang, Ning, Jin, Caining, Long, Mark D., Rajabi, Hasan, Yasumizu, Yota, Fushimi, Atsushi, Yamashita, Nami, Hagiwara, Masayuki, Zheng, Rongbin, Wang, Jin, Kui, Ling, Singh, Harpal, Kharbanda, Surender, Hu, Qiang, Liu, Song, Kufe, Donald
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406273/
https://ncbi.nlm.nih.gov/pubmed/32427590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137112
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