A carregar...
Spontaneous Polyploids and Antimutators Compete During the Evolution of Saccharomyces cerevisiae Mutator Cells
Mutations affecting DNA polymerase exonuclease domains or mismatch repair (MMR) generate “mutator” phenotypes capable of driving tumorigenesis. Cancers with both defects exhibit an explosive increase in mutation burden that appears to reach a threshold, consistent with selection acting against furth...
Na minha lista:
| Publicado no: | Genetics |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7404223/ https://ncbi.nlm.nih.gov/pubmed/32513814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303333 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|