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Emergence of DNA Polymerase ε Antimutators That Escape Error-Induced Extinction in Yeast
DNA polymerases (Pols) ε and δ perform the bulk of yeast leading- and lagging-strand DNA synthesis. Both Pols possess intrinsic proofreading exonucleases that edit errors during polymerization. Rare errors that elude proofreading are extended into duplex DNA and excised by the mismatch repair (MMR)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583996/ https://ncbi.nlm.nih.gov/pubmed/23307893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.146910 |
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