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Emergence of DNA Polymerase ε Antimutators That Escape Error-Induced Extinction in Yeast
DNA polymerases (Pols) ε and δ perform the bulk of yeast leading- and lagging-strand DNA synthesis. Both Pols possess intrinsic proofreading exonucleases that edit errors during polymerization. Rare errors that elude proofreading are extended into duplex DNA and excised by the mismatch repair (MMR)...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583996/ https://ncbi.nlm.nih.gov/pubmed/23307893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.146910 |
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