Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

Cells rely on a network of conserved pathways to govern DNA replication fidelity. Loss of polymerase proofreading or mismatch repair elevates spontaneous mutation and facilitates cellular adaptation. However, double mutants are inviable, suggesting that extreme mutation rates exceed an error thresho...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Herr, Alan J., Ogawa, Masanori, Lawrence, Nicole A., Williams, Lindsey N., Eggington, Julie M., Singh, Mallika, Smith, Robert A., Preston, Bradley D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188538/
https://ncbi.nlm.nih.gov/pubmed/22022273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002282
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