Impact of I(SK) Voltage and Ca(2+)/Mg(2+)-Dependent Rectification on Cardiac Repolarization

Cardiac small conductance Ca(2+)-activated K(+) (SK) channels are activated solely by Ca(2+), but the SK current (I(SK)) is inwardly rectified. However, the impact of inward rectification in shaping action potentials (APs) in ventricular cardiomyocytes under β-adrenergic stimulation or in disease st...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Bronk, Peter, Kim, Tae Yun, Polina, Iuliia, Hamilton, Shanna, Terentyeva, Radmila, Roder, Karim, Koren, Gideon, Terentyev, Dmitry, Choi, Bum-Rak
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399499/
https://ncbi.nlm.nih.gov/pubmed/32668235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.022
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