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NCX-Mediated Subcellular Ca(2+) Dynamics Underlying Early Afterdepolarizations in LQT2 Cardiomyocytes
Long QT syndrome type 2 (LQT2) is a congenital disease characterized by loss of function mutations in hERG potassium channels (I(Kr)). LQT2 is associated with fatal ventricular arrhythmias promoted by triggered activity in the form of early afterdepolarizations (EADs). We previously demonstrated tha...
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| 發表在: | Biophys J |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140381/ https://ncbi.nlm.nih.gov/pubmed/30173888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.004 |
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