Sarcoplasmic reticulum Ca(2+) release is both necessary and sufficient for SK channel activation in ventricular myocytes

SK channels are upregulated in human patients and animal models of heart failure (HF). However, their activation mechanism and function in ventricular myocytes remain poorly understood. We aim to test the hypotheses that activation of SK channels in ventricular myocytes requires Ca(2+) release from...

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Bibliografski detalji
Glavni autori: Terentyev, Dmitry, Rochira, Jennifer A., Terentyeva, Radmila, Roder, Karim, Koren, Gideon, Li, Weiyan
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Cardiac Excitation and Contraction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949063/
https://ncbi.nlm.nih.gov/pubmed/24381116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00621.2013
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