Sarcoplasmic reticulum Ca(2+) release is both necessary and sufficient for SK channel activation in ventricular myocytes

SK channels are upregulated in human patients and animal models of heart failure (HF). However, their activation mechanism and function in ventricular myocytes remain poorly understood. We aim to test the hypotheses that activation of SK channels in ventricular myocytes requires Ca(2+) release from...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Terentyev, Dmitry, Rochira, Jennifer A., Terentyeva, Radmila, Roder, Karim, Koren, Gideon, Li, Weiyan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2013
Θέματα:
Cardiac Excitation and Contraction
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949063/
https://ncbi.nlm.nih.gov/pubmed/24381116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00621.2013
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