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Sarcoplasmic reticulum Ca(2+) release is both necessary and sufficient for SK channel activation in ventricular myocytes
SK channels are upregulated in human patients and animal models of heart failure (HF). However, their activation mechanism and function in ventricular myocytes remain poorly understood. We aim to test the hypotheses that activation of SK channels in ventricular myocytes requires Ca(2+) release from...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949063/ https://ncbi.nlm.nih.gov/pubmed/24381116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00621.2013 |
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