SK channel enhancers attenuate Ca(2+)-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR

AIMS: Plasmamembrane small conductance Ca(2+)-activated K(+ )(SK) channels were implicated in ventricular arrhythmias in infarcted and failing hearts. Recently, SK channels were detected in the inner mitochondria membrane (IMM) (mSK), and their activation protected from acute ischaemia-reperfusion i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cardiovasc Res
Päätekijät: Kim, Tae Yun, Terentyeva, Radmila, Roder, Karim H. F., Li, Weiyan, Liu, Man, Greener, Ian, Hamilton, Shanna, Polina, Iuliia, Murphy, Kevin R., Clements, Richard T., Dudley, Samuel C., Koren, Gideon, Choi, Bum-Rak, Terentyev, Dmitry
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852621/
https://ncbi.nlm.nih.gov/pubmed/28096168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx005
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