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BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation
Microtubules display dynamic turnover during cell migration, leading to cell contractility and focal adhesion maturation regulated by Rho guanosine triphosphatase activity. This interplay between microtubules and actomyosin is mediated by guanine nucleotide exchange factor (GEF)–H1 released after mi...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7399486/ https://ncbi.nlm.nih.gov/pubmed/32789168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1534 |
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