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Phosphorylation-mediated regulation of GEFs for RhoA

Spatio-temporal control of RhoA GTPase is critical for regulation of cell migration, attachment to extracellular matrix, and cell–cell adhesions. Activation of RhoA is mediated by guanine nucleotide exchange factors (GEFs), a diverse family of enzymes that are controlled by multiple signaling pathwa...

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Hlavní autoři: Patel, Maulik, Karginov, Andrei V
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974788/
https://ncbi.nlm.nih.gov/pubmed/24589508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.28058
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