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Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization
The small GTPase RhoA is involved in cell morphology and migration. RhoA activity is tightly regulated in time and space and depends on guanine exchange factors (GEFs). However, the kinetics and subcellular localization of GEF activity towards RhoA are poorly defined. To study the mechanism underlyi...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592971/ https://ncbi.nlm.nih.gov/pubmed/26435194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14693 |
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