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Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization

The small GTPase RhoA is involved in cell morphology and migration. RhoA activity is tightly regulated in time and space and depends on guanine exchange factors (GEFs). However, the kinetics and subcellular localization of GEF activity towards RhoA are poorly defined. To study the mechanism underlyi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: van Unen, Jakobus, Reinhard, Nathalie R., Yin, Taofei, Wu, Yi I., Postma, Marten, Gadella, Theodorus W.J., Goedhart, Joachim
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592971/
https://ncbi.nlm.nih.gov/pubmed/26435194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14693
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