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Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF

Junctional adhesion molecule A (JAM-A) is a broadly expressed adhesion molecule that regulates cell–cell contacts and facilitates leukocyte transendothelial migration. The latter occurs through interactions with the integrin LFA-1. Although we understand much about JAM-A, little is known regarding t...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Scott, David W., Tolbert, Caitlin E., Burridge, Keith
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850030/
https://ncbi.nlm.nih.gov/pubmed/26985018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-12-0833
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