Načítá se...

The RhoGEF domain of p210 Bcr-Abl activates RhoA and is required for transformation

The BCR-ABL oncogene encodes an in-frame fusion protein containing NH(2)-terminal sequences derived from Bcr and COOH-terminal sequences derived from Abl. Bcr contains a centrally located RhoGEF domain that is retained within p210 Bcr-Abl. Although this domain is subject to autoinhibition in the con...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sahay, S, Pannucci, NL, Mahon, GM, Rodriguez, PL, Megjugorac, NJ, Kostenko, EV, Ozer, HL, Whitehead, IP
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676674/
https://ncbi.nlm.nih.gov/pubmed/17922031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210841
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!