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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells

Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Goedhart, Joachim, van Unen, Jakobus
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548299/
https://ncbi.nlm.nih.gov/pubmed/28521592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1302551
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