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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells

Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...

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Detalles Bibliográficos
Publicado en:Small GTPases
Autores principales: Goedhart, Joachim, van Unen, Jakobus
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548299/
https://ncbi.nlm.nih.gov/pubmed/28521592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1302551
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