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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells

Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...

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Bibliografische gegevens
Gepubliceerd in:Small GTPases
Hoofdauteurs: Goedhart, Joachim, van Unen, Jakobus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548299/
https://ncbi.nlm.nih.gov/pubmed/28521592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1302551
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