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Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells

Much of our current knowledge of Rho GTPase networks and the regulation by Rho guanine exchange factors (Rho GEFs) and Rho GTPase activating proteins (Rho GAPs) is based on population-based techniques. Over the last decades, technologies that enable single cell analysis with high spatial and tempora...

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Dades bibliogràfiques
Publicat a:Small GTPases
Autors principals: Goedhart, Joachim, van Unen, Jakobus
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548299/
https://ncbi.nlm.nih.gov/pubmed/28521592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1302551
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