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GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA
The RhoA GTPase plays a vital role in assembly of contractile actin-myosin filaments (stress fibers) and of associated focal adhesion complexes of adherent monolayer cells in culture. GEF-H1 is a microtubule-associated guanine nucleotide exchange factor that activates RhoA upon release from microtub...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366883/ https://ncbi.nlm.nih.gov/pubmed/18287519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1269 |
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