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GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

The RhoA GTPase plays a vital role in assembly of contractile actin-myosin filaments (stress fibers) and of associated focal adhesion complexes of adherent monolayer cells in culture. GEF-H1 is a microtubule-associated guanine nucleotide exchange factor that activates RhoA upon release from microtub...

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Main Authors: Chang, Yuan-Chen, Nalbant, Perihan, Birkenfeld, Jörg, Chang, Zee-Fen, Bokoch, Gary M.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366883/
https://ncbi.nlm.nih.gov/pubmed/18287519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1269
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