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GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases
Formation of the mitotic cleavage furrow is dependent upon both microtubules and activity of the small GTPase RhoA. GEF-H1 is a microtubule-regulated exchange factor that couples microtubule dynamics to RhoA activation. GEF-H1 localized to the mitotic apparatus in HeLa cells, particularly at the tip...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965589/ https://ncbi.nlm.nih.gov/pubmed/17488622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.03.014 |
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