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Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome

Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. Mitochon...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Gella, Alejandro, Prada-Dacasa, Patricia, Carrascal, Montserrat, Urpi, Andrea, González-Torres, Melania, Abian, Joaquin, Sanz, Elisenda, Quintana, Albert
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399339/
https://ncbi.nlm.nih.gov/pubmed/32850799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00660
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