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Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome

Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. Mitochon...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Gella, Alejandro, Prada-Dacasa, Patricia, Carrascal, Montserrat, Urpi, Andrea, González-Torres, Melania, Abian, Joaquin, Sanz, Elisenda, Quintana, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399339/
https://ncbi.nlm.nih.gov/pubmed/32850799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00660
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