Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome

Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. Mitochon...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Gella, Alejandro, Prada-Dacasa, Patricia, Carrascal, Montserrat, Urpi, Andrea, González-Torres, Melania, Abian, Joaquin, Sanz, Elisenda, Quintana, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399339/
https://ncbi.nlm.nih.gov/pubmed/32850799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00660
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