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Inferring population dynamics from single-cell RNA-sequencing time series data

Recent single-cell RNA-sequencing studies have suggested that cells follow continuous transcriptomic trajectories in an asynchronous fashion during development. However, observations of cell flux along trajectories are confounded with population size effects in snapshot experiments and are therefore...

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Détails bibliographiques
Publié dans:Nat Biotechnol
Auteurs principaux: Fischer, David S., Fiedler, Anna K., Kernfeld, Eric M., Genga, Ryan M.J., Bastidas-Ponce, Aimée, Bakhti, Mostafa, Lickert, Heiko, Hasenauer, Jan, Maehr, Rene, Theis, Fabian J.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397487/
https://ncbi.nlm.nih.gov/pubmed/30936567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0088-0
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