Inferring population dynamics from single-cell RNA-sequencing time series data

Recent single-cell RNA-sequencing studies have suggested that cells follow continuous transcriptomic trajectories in an asynchronous fashion during development. However, observations of cell flux along trajectories are confounded with population size effects in snapshot experiments and are therefore...

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Pubblicato in:Nat Biotechnol
Autori principali: Fischer, David S., Fiedler, Anna K., Kernfeld, Eric M., Genga, Ryan M.J., Bastidas-Ponce, Aimée, Bakhti, Mostafa, Lickert, Heiko, Hasenauer, Jan, Maehr, Rene, Theis, Fabian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397487/
https://ncbi.nlm.nih.gov/pubmed/30936567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0088-0
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