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A single-cell transcriptomic atlas of thymus organogenesis resolves cell types and developmental maturation

Thymus development is critical to the adaptive immune system, yet a comprehensive transcriptional framework capturing thymus organogenesis at single cell resolution is still needed. We applied single-cell RNA-seq to capture eight days of thymus development, perturbations of T-cell receptor rearrange...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Kernfeld, Eric M, Genga, Ryan MJ, Neherin, Kashfia, Magaletta, Margaret E, Xu, Ping, Maehr, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013397/
https://ncbi.nlm.nih.gov/pubmed/29884461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.015
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