A carregar...
Oncogenic RAS isoforms show a hierarchical requirement for SOS2 to drive transformation
About a third of tumors harbor activating mutations in HRAS, NRAS, or KRAS, genes encoding guanine triphosphatases (GTPases) of the RAS family. In these tumors, wild-type RAS signaling cooperates with mutant RAS to promote downstream effector activation. This cooperation between wild-type and mutant...
Na minha lista:
| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7396125/ https://ncbi.nlm.nih.gov/pubmed/30181243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aar8371 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|