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The Role of Wild-Type RAS in Oncogenic RAS Transformation
The RAS family of oncogenes (HRAS, NRAS, and KRAS) are among the most frequently mutated protein families in cancers. RAS-mutated tumors were originally thought to proliferate independently of upstream signaling inputs, but we now know that non-mutated wild-type (WT) RAS proteins play an important r...
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| Pubblicato in: | Genes (Basel) |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8146411/ https://ncbi.nlm.nih.gov/pubmed/33924994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12050662 |
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