Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

The current COVID-19 pandemic is caused by the SARS-CoV-2 betacoronavirus, which utilizes its highly glycosylated trimeric Spike protein to bind to the cell surface receptor ACE2 glycoprotein and facilitate host cell entry. We utilized glycomics-informed glycoproteomics to characterize site-specific...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:bioRxiv
Egile Nagusiak: Zhao, Peng, Praissman, Jeremy L., Grant, Oliver C., Cai, Yongfei, Xiao, Tianshu, Rosenbalm, Katelyn E., Aoki, Kazuhiro, Kellman, Benjamin P., Bridger, Robert, Barouch, Dan H., Brindley, Melinda A., Lewis, Nathan E., Tiemeyer, Michael, Chen, Bing, Woods, Robert J., Wells, Lance
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386495/
https://ncbi.nlm.nih.gov/pubmed/32743578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.25.172403
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