Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and facilitate host cell entry. We utilized glycomics-informed glycoproteomics to characterize site-specific microheterogeneity...

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Bibliografiset tiedot
Julkaisussa:Cell Host Microbe
Päätekijät: Zhao, Peng, Praissman, Jeremy L., Grant, Oliver C., Cai, Yongfei, Xiao, Tianshu, Rosenbalm, Katelyn E., Aoki, Kazuhiro, Kellman, Benjamin P., Bridger, Robert, Barouch, Dan H., Brindley, Melinda A., Lewis, Nathan E., Tiemeyer, Michael, Chen, Bing, Woods, Robert J., Wells, Lance
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier Inc. 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443692/
https://ncbi.nlm.nih.gov/pubmed/32841605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.08.004
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