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Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
Binding of the spike protein of SARS-CoV-2 to the human angiotensin-converting enzyme 2 (ACE2) receptor triggers translocation of the virus into cells. Both the ACE2 receptor and the spike protein are heavily glycosylated, including at sites near their binding interface. We built fully glycosylated...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126795/ https://ncbi.nlm.nih.gov/pubmed/33903171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100425118 |
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