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Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
Binding of the spike protein of SARS-CoV-2 to the human angiotensin-converting enzyme 2 (ACE2) receptor triggers translocation of the virus into cells. Both the ACE2 receptor and the spike protein are heavily glycosylated, including at sites near their binding interface. We built fully glycosylated...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126795/ https://ncbi.nlm.nih.gov/pubmed/33903171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100425118 |
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