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Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

Receptor binding studies on sarbecoviruses would benefit from an available toolkit of recombinant spike proteins, or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric Receptor Binding Domain (RBD) proteins would be suitable candidates to...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Bouwman, Kim M., Tomris, Ilhan, Turner, Hannah L., van der Woude, Roosmarijn, Shamorkina, Tatiana M., Bosman, Gerlof P., Rockx, Barry, Herfst, Sander, Snijder, Joost, Haagmans, Bart L., Ward, Andrew B., Boons, Geert-Jan, de Vries, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895411/
https://ncbi.nlm.nih.gov/pubmed/33556147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009282
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