Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

Receptor binding studies on sarbecoviruses would benefit from an available toolkit of recombinant spike proteins, or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric Receptor Binding Domain (RBD) proteins would be suitable candidates to...

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Udgivet i:PLoS Pathog
Main Authors: Bouwman, Kim M., Tomris, Ilhan, Turner, Hannah L., van der Woude, Roosmarijn, Shamorkina, Tatiana M., Bosman, Gerlof P., Rockx, Barry, Herfst, Sander, Snijder, Joost, Haagmans, Bart L., Ward, Andrew B., Boons, Geert-Jan, de Vries, Robert P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895411/
https://ncbi.nlm.nih.gov/pubmed/33556147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009282
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