Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

Receptor binding studies on sarbecoviruses would benefit from an available toolkit of recombinant spike proteins, or domains thereof, that recapitulate receptor binding properties of native viruses. We hypothesized that trimeric Receptor Binding Domain (RBD) proteins would be suitable candidates to...

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Pubblicato in:PLoS Pathog
Autori principali: Bouwman, Kim M., Tomris, Ilhan, Turner, Hannah L., van der Woude, Roosmarijn, Shamorkina, Tatiana M., Bosman, Gerlof P., Rockx, Barry, Herfst, Sander, Snijder, Joost, Haagmans, Bart L., Ward, Andrew B., Boons, Geert-Jan, de Vries, Robert P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895411/
https://ncbi.nlm.nih.gov/pubmed/33556147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009282
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