Potent and rapid reversal of the von Willebrand factor inhibitor aptamer BT200

BACKGROUND: BT200, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis in cynomolgus monkeys. It is being developed for secondary prevention of arterial thrombosis such as stroke or myocardial infarction...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Thromb Haemost
Egile Nagusiak: Zhu, Shuhao, Gilbert, James C., Liang, Zicai, Kang, Daiwu, Li, Ming, Tarantino, Paul M., Jilma, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
THROMBOSIS
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384040/
https://ncbi.nlm.nih.gov/pubmed/32275107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14822
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