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Potent and rapid reversal of the von Willebrand factor inhibitor aptamer BT200
BACKGROUND: BT200, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis in cynomolgus monkeys. It is being developed for secondary prevention of arterial thrombosis such as stroke or myocardial infarction...
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| 出版年: | J Thromb Haemost |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7384040/ https://ncbi.nlm.nih.gov/pubmed/32275107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14822 |
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