The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor-mediated ex vivo platelet function in ST-elevation and non-ST-elevation acute myocardial infarction

Antzeko izenburuak

• Potent and rapid reversal of the von Willebrand factor inhibitor aptamer BT200
  nork: Zhu, Shuhao, et al.
  Argitaratua: (2020)
• Novel aptamer to von Willebrand factor A1 domain (TAGX-0004) shows total inhibition of thrombus formation superior to ARC1779 and comparable to caplacizumab
  nork: Sakai, Kazuya, et al.
  Argitaratua: (2019)
• The development and characterization of a long acting anti‐thrombotic von Willebrand factor (VWF) aptamer
  nork: Zhu, Shuhao, et al.
  Argitaratua: (2020)
• A Structural Explanation for the Antithrombotic Activity of ARC1172, a DNA Aptamer that Binds von Willebrand Factor Domain A1
  nork: Huang, Ren-Huai, et al.
  Argitaratua: (2009)
• The aptamer BT200 blocks von Willebrand factor and platelet function in blood of stroke patients
  nork: Kovacevic, Katarina D., et al.
  Argitaratua: (2021)